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Generic Viagra is a medication that you may know about but more likely have heard of its brand name counterpart (Pfizer). Generic Viagra uses the same active ingredients that have been shown to effectively treat erectile dysfunction. It also has other uses, including pulmonary hypertension and altitude sickness in both men and women. This medication allows men to enjoy sexual intercourse with their partners by helping treat the symptoms of erectile dysfunction, although it cannot cure the condition. Many medical practitioners prescribe generic Viagra for treatment while they are attempting to diagnose the underlying cause of the ED symptoms.

 

 

Another benefit of generic Viagra (known as sildenafil) is that it allows you to enjoy a close relationship with someone special and can help keep relationships strong during a stressful period. It can be frustrating and even frightening to have a condition like ED that you can't control and can't determine the cause. This medication can help you overcome those feelings and even allow you to regain control of your life again. If your doctor has not prescribed any medication for your ED, you can ask him or her about sildenafil and find out if you are a candidate for the drug. Enjoy a better quality of life and feel in control again.

What is Sildenafil or Viagra?
What is Sildenafil? Sildenafil is a medication from the PDE5 inhibitor class of medications and it is better known as Viagra. However, this is somewhat of a fallacy as not all Sildenafil is Viagra. For example, in some countries, Sildenafil is sold under different brand names (Kamagra, Fildena, Eriacta, Caverta, Aurogra, Intagra, Penegra, Silagra, Silvitra, Suhagra, Zenegra etc) and when it is used for pulmonary hypertension, Sildenafil comes under the name Revatio. However, at this article, when we are talking about Sildenafil, we are talking about Viagra, unless specifically noted otherwise.

As this website is envisioned as the place to come to if you are looking for objective information about Sildenafil, there is no way that we can neglect the very mechanism of action of this erectile dysfunction medication, the first ED medication that has been approved by the FDA.

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However, before we can get into the details about how Sildenafil works, we need to talk about the condition itself, erectile dysfunction. The normal healthy way in which men reach erections goes like this. First of all, nitric oxide is released when the man gets sexually aroused. The release of this compound triggers the release and the action of a chemical known as cGMP. This chemical relaxes and dilates the blood vessels in the genital area, which leads to the blood getting into the penis in large amounts.

Once the spongy tissue in the penis, known as corpus cavernosum gets filled with blood, the hydraulic effect of blood results in an erection, which is then kept until the release, i.e. until the orgasm.What happens in erectile dysfunction is that the functioning of cGMP is inhibited by an enzyme known as PDE5. There is a number of different enzymes in the body that can cause the constriction of blood vessels due to their action on cGMP and similar chemicals. The PDE5 is responsible for inhibiting the dilation of blood vessels that lead the blood into the corpus cavernosum.

The increased levels and the enhanced functioning of PDE5 can be caused by a number of factors, ranging from different medical conditions, to anxiety and it can sometimes be a side effect of other medications (the most common class of drugs that results in this are SSRI antidepressants, for example).This is in most cases the reason for erectile dysfunction and in such cases Sildenafil is of great help.The reason for this is that Sildenafil inhibits the functioning of the PDE5 enzyme, which is how the class of drugs got its name, the PDE5 inhibitors, including Sildenafil as the first one, as well as tadalafil and vardenafil which followed after several years.

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As PDE5 is inhibited, cGMP is allowed to work properly, causing the blood vessels to dilate. The corpus cavernosum gets filled with blood and the erection occurs.
The effects of Sildenafil include the maintaining of the erection as well.It has to be noted that the sexual arousal is still necessary for the erection to happen and you should not worry that you will get an erection that will be present no matter what, which is something that is more of a problem than a result. This is because cGMP does not start to act unless nitric oxide is released and it gets released only when the man is sexually aroused.

This is, in short, how Viagra (Sildenafil) works and we hope that we have cleared up a thing or two about the mechanism of action of this ED medication. Other ED medications (Cialis (Tadalafil), Levitra (Vardenafil)) work in pretty much the same way, mostly because of the fact that they have been developed taking clues from Sildenafil, the original ED drug.